Ise
proper noun
The place with Italy force is a place known as Ise. It's a region of Japan that has a nice peninsula, I think. Going straight to the reading for this one may be your best bet.
いせ
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own. Just watch out, because this uses the せ, not the せい you're used to seeing.
伊勢神宮には、一度行ってみた方がいいよ。
You should go see the Ise Shrine once.