Shop, Store
noun
The kanji and the word are exactly the same. That means they share meanings as well.
みせ
Since this word is made up of a single kanji, it should use the kun'yomi reading. When learning the kanji, you didn't learn that reading, so here's a mnemonic to help you with this word: Think of your favorite shop. Okay, now imagine yourself going to it. When you arrive, the entire shop is totally missing (みせ). Feel the shock and awe of this. It's as if it picked up and left overnight. No building, no anything. Just missing.
一人で店に入りました。
I entered the store alone.
店の入り口には大きいメニューがあります。
There is a large menu at the entrance of the store.
この店は大人の男の人に人気があります。
This store is popular with adult men.