Painkiller
noun
痛み is "pain." 止める is "to stop." What stops pain if you use it? How about a painkiller.
いたみどめ
The reading is 痛み and 止める put together into one word. Not too painful, right? Just remember the rendaku on the ど.
頭痛がひどいので、痛み止めを飲みました。
I had a bad headache, so I took a painkiller.
痛み止めが効いてきて、少し楽になりました。
The painkiller is starting to take effect, and I feel a bit better.
薬局で痛み止めを買ってきてもらえませんか？
Could you pick up some painkillers for me from the pharmacy?
彼は痛み止めを飲んで、また畑を耕し始めた。
He took a painkiller and kept plowing the field.