Chain, Chaining, Connection
noun, verbal noun
If you take along a chain with you it's still a chain, it's just moving somewhere new.
れんさ
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own.
まずはこの負の連鎖を断ち切る必要があります。
First, there's a need to break this vicious chain of unfortunate events.